Worm Breeder's Gazette 9(3): 27
These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.
I have been collecting spontaneous uncoordinated mutants with the aim of cloning genes by transposon tagging. It seems desirable to exchange information on 'tagged' genes. Gifts to this lab have been greatly appreciated. Anyone interested in any of these genes should not hesitate to get in touch. I have pursued three genes: unc-13, 153) is associated with a rearrangement (see accompanying report). Unc-30(bx7) does not appear to be associated with a Tc1 insertion. Unc-31 seems to be a 'hot spot' for spontaneous mutation in TR679. Additional alleles have been obtained at Columbia. A spontaneous revertant of e2126 has been isolated. E2126 has been outcrossed nine times to Bristol. A dpy-20(e1282)unc-26(e205) double has been constructed and used to select 21 dpy recombinants near the unc-31 locus in the multiply outcrossed strain. Mapping of linked Tc1 elements will begin immediately. Unc-31 alleles are pumping constitutive (1); all mutants examined pump rapidly and continuously. Mutants are also sluggish. The nature of the gene product is a mystery.