Worm Breeder's Gazette 9(1): 39

These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.

Some Chromosome Rearrangements

C. Kari, M. Winter, and B. Herman

A new X chromosome-duplication, called mnDp57(X;I), carries the wild-
type alleles of unc-2, unc-20, 
not carry the wild-type alleles 
of dpy-3 or dpy-8, which flank this region.  The duplication is 
situated less than one map unit from unc-54 I; it does not have much 
effect on crossing over on linkage group (LG) I, and it is homozygous 
viable.  Duplication-bearing males mate well.
The autosomal duplication mnDp37(III;f) is very large, extending 
from the left of dpy-1 (but not including unc-45), to the right of unc-
25 (but not including unc-64).  Because of the way in which it was 
made, it carries the mutation unc-32(e189).  It occasionally 
recombines with the normal chromosome III.  We have also obtained 
variants of mnDp37, some spontaneous and some apparently induced by 
gamma rays.  One spontaneous variant is called mnDp40(III;f); it 
carries the wild-type alleles of dpy-1, 
s several markers farther to the 
right, such as lon-1, unc-36 and unc-50.  
Hermaphrodites carrying mnDp40 give more nullo-duplication self-
progeny than do hermaphrodites carrying mnDp37.The X-ray-induced 
translocation mnT4(III;IV) was identified by virtue of its property of 
reducing the apparent recombination between dpy-1 and unc-32 to less 
than 1%.  Recombination on LGIV is not greatly affected.  There is 
strong pseudolinkage between dpy-1 III and unc-8 IV (about 1% 
recombination), suggesting that the latter is in the neighborhood of a 
breakpoint.  We have evidence for significant nondisjunction between 
mnT4 and the normal chromosome III, leading to animals that are