Worm Breeder's Gazette 7(2): 69

These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.

Arylesterases in C. elegans

B. Beguet, C. Bosch

In the wild-type N2 , an E.C. arylesterase activity has 
been revealed in the entire proteins extracted by means of sonication 
without the help of any detergent.
The total activity of the wild-type for adult hermaphrodites is 148 
International Units/liter/mg of proteins.
The filtration on Sephadex gel and the electrophoresis have showed 
that the greater part of this activity (80% to 85% ) amounted to about 
75,000 daltons, the other one (15% to 20%) to about 120,000 - 150,000 
Forty mutants that can resist a substance inhibiting the E.C. 
activities, have been isolated.  These resistance mutants can be put 
together into 3 groups according to their total activitie: 100% , 85% 
and 50% of the rate of activity of the wild-type.
The reproductive potential of the mutants belonging to the last two 
groups is lower than that of the wild-type (decrease of 80%).
The function of a certain number of molecular forms with an E.C.  3.
1.1.2.  activity may be considered as far as reproduction is concerned.