Worm Breeder's Gazette 7(1): 92
These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.
We have been isolating and characterizing dominant mutants of C. elegans. Dominant mutations are convenient genetic markers and can be useful in generating deficiencies; in addition, dominant mutations may define genes that are members of multigene families (Greenwald and Horvitz, Genetics, 96, 147, 1980). Dominant mutants were obtained by mutagenizing either N2 males or hermaphrodites with EMS and looking for mutants among the F1 progeny using the dissecting microscope. The map below shows the positions of dominant mutations that define new genes or that are in genes for which dominant alleles have not previously been reported. The phenotypes of these mutants are as [See Figure 1]