Worm Breeder's Gazette 7(1): 92

These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.

Some Newly Isolated Dominant Mutants of C. elegans

J. Park, B. Horvitz

Figure 1

We have been isolating and characterizing dominant mutants of C.  
elegans.  Dominant mutations are convenient genetic markers and can be 
useful in generating deficiencies; in addition, dominant mutations may 
define genes that are members of multigene families (Greenwald and 
Horvitz, Genetics, 96, 147, 1980).  Dominant mutants were obtained by 
mutagenizing either N2 males or hermaphrodites with EMS and looking 
for mutants among the F1 progeny using the dissecting microscope.  The 
map below shows the positions of dominant mutations that define new 
genes or that are in genes for which dominant alleles have not 
previously been reported.  The phenotypes of these mutants are as 

[See Figure 1]

Figure 1