Worm Breeder's Gazette 5(1): 10
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Dear Dr. Edgar: 28.11.1979. Probably you have got our two papers for News Letters (dealing with Precocene in Nematodes and Bal-X-chromosome, respectively. I should like to complete the Bal-X-1 paper with some recent data arriving from Szeged today. The genotype of hermaphrodites of the stock: dpy-8( e1321) * unc-3(e151) over * lon-2(e678) *.The distribution of the self- progeny was the followings: [See Figure 1] The occurrence of males having one of the X chromosomes alternatively among P1 progeny indicate the the presence of Bal-X-1 chromosome causes some anomaly in meiotic pairing of the homologs.The reason of this could be i.) The presence of a dominant him mutation ( homozygous lethal) nearby to the lon 2 marker; ii.) chromosome aberration, probably translocation. Considering,that we could not manage to ride of this dominant effect by several outcrosses ( recombination) we prefer the second hypothesis to test. Best regards: Andras Fodor (BRC, Szeged)