Worm Breeder's Gazette 2(2): 24b
These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.
In reversion studies of the null mutant E1214 of the paramyosin gene unc-15 a partial revertant has been isolated in which paramyosin is partially restored. This is due to a second mutation, e1464, which maps in the cluster of LG III. In addition, e1464, is able to suppress certain isolates and not others in several different complementation groups, some of which do not involve muscle. These and other observations are consistent with the hypothesis that e1464 results in informational suppression possibly of chain-terminating mutations, which is perhaps mediated by an altered tRNA species.