Worm Breeder's Gazette 16(4): 15 (October 1, 2000)

These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.

Update on the C. elegans database WormBase

The WormBase Consortium

Cold Spring Harbor Laboratory, Sanger Centre, Washington University, NCBI, Caltech

WormBase (www.wormbase.org) is an international consortium of biologists
and computer scientists dedicated to providing the research community
with accurate, current, accessible information concerning the genetics,
genomics and biology of C. elegans and some related nematodes.  WormBase
builds upon the existing ACeDB database of the C. elegans genome by
providing curation from the literature, an expanded range of content and
a user friendly web interface.  The team that developed and maintained
ACeDB (Richard Durbin, Jean Thierry-Mieg) remains an important part of
WormBase.  Lincoln Stein and colleagues at Cold Spring Harbor are
leading the effort to develop the user interface, including
visualization tools for the genome and genetic map.  Teams at Sanger
Centre (led by Richard Durbin) and the Genome Sequencing Center at
Washington University, St. Louis (led by John Spieth) continue to curate
the genomic sequence.  Jean and Danielle Thierry-Mieg at NCBI spearhead
importation of large-scale data sets from other projects.  Paul
Sternberg and colleagues at Caltech will curate new data including cell
function in development, behavior and physiology, gene expression at a
cellular level; and gene interactions.  Paul Sternberg assumes overall
responsibility for WormBase, and is delighted to hear feedback of any

WormBase has recently received major funding from the National Human
Genome Research Institute at the US National Institutes of Health, and
also receives support from the National Library of Medicine/NCBI and the
British Medical Research Council.  

WormBase is an expansion of existing efforts, and as such continues to
need you help and feedback.  Even with the increased scope and funding,
all past contributors to ACeDB remain involved.  The Caenorhabditis
Genetics Center (Jonathan Hodgkin and Sylvia Martinelli) collaborate
with WormBase to curate the genetic map and related topics. Ian Hope and
colleagues continue to supply expression data to WormBase.  Leon Avery
will continue his superb website and serves as one advisor to WormBase. 
While the major means of access to WormBase is via the world wide web,
downloadable versions of WormBase as well as the acedb software engine
will continue to be available.