Worm Breeder's Gazette 10(1): 58

These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.

Sequence of the Glutathione S-transferase P subunit of C. elegans, or A Step Towards the Complete Sequence of the C. elegans Genome

J. Yochem, K. Weston and Iva Greenwald

Figure 1

In the process of completing the sequence of lin-12, we 
inadvertently obtained the sequence of the adjacent gene on the 3' 
side of lin-12.  It is oriented in the opposite direction relative to 
lin-12.  (We have data indicating that lin-12 runs 5' to 3' with 
respect to the genetic map.) The sequence presented below is a 
composite of genomic and cDNA sequence data; the cDNAs were obtained 
from a library kindly provided by Julie Ahringer and Judith Kimble.  
The predicted product is 40% identical to rat liver glutathione S-
transferase P subunit (Suguoka et al., NAR 13: 6049, 1985); the degree 
of homology is higher if conservative substitutions are taken into 
account.  Identical amino acids are boxed.  The data indicate that 
there is a splice joining an exon (277-end) to a 5' exon(s).
[See Figure 

Figure 1