CGC Bibliography Paper 5718

WorfDB: the Caenorhabditis elegans ORFeome database.

Vaglio P, Lamesch P, Reboul J, Rual JF, Martinez M, Hill D, Vidal M

Medline:

12519990

Citation:

Nucleic Acids Research 31: 237-240 2003

Type:

ARTICLE

Genes:

Abstract:

WorfDB (Worm ORFeome DataBase; http://worfdb.dfci.harvard.edu) was created to integrate and disseminate the data from the cloning of complete set of similar to19000 predicted protein-encoding Open Reading Frames (ORFs) of Caenorhabditis elegans ( also referred to as the 'worm ORFeome'). WorfDB serves as a central data repository enabling the scientific community to search for availability and quality of cloned ORFs. So far, ORF sequence tags (OSTs) obtained for all individual clones have allowed exon structure corrections for similar to3400 ORFs originally predicted by the C. elegans sequencing consortium. In addition, we now have OSTs for similar to4300 predicted genes for which no ESTs were available. The database contains this OST information along with data pertinent to the cloning process. WorfDB could serve as a model database for other metazoan ORFeome cloning projects.