CGC Bibliography Paper 5712

Cost-free longevity in mice?

Lithgow GJ, Gill MS

Medline:

Citation:

Nature 421: 125-126 2003

Type:

REVIEW

Genes:

daf-2

Abstract:

Studies of worms have revealed hundreds of proteins that, when mutated, extend lifespan. Can this work tell us anything about mammalian ageing? A look at the effects of one such protein on lab mice suggests that it can.