CGC Bibliography Paper 5697

Caenorhabditis elegans operons: form and function.

Blumenthal T, Gleason KS

Medline:

12560808

Citation:

Nature Reviews Genetics 4: 110-118 2003

Type:

REVIEW

Genes:

ced-9 coq-1 coq-3 coq-4 coq-5 cox-15 cyp-1 cyp-5 cpy-9 cpy-11 cpy-12 cpy-13 cpy-14 cpy-16 cyt-1 deg-3 des-2 dom-3 fib-1 gpd-2 gpd-3 grp-1 inf-1 leo-1 lin-15 lin-53 mai-1 mes-3 num-1 npp-4 pdi-1 rba-1 rba-2 rpa-0 rpa-1 rpa-3 rps-4 rps-16 set-2 sir-2.1 tpi-1 uaf-2

Abstract:

Nematodes are unusual among animals in having a substantial proportion of their genes arranged in polycistronic clusters that are similar to bacterial operons. Recently, a nearly complete database of the Caenorhabditis elegans genes that are transcribed in operons has been produced. Analysis of this database has identified the types of genes that are contained in the operons and the extent to which operons co-regulate genes of related function.