CGC Bibliography Paper 5684

Cell polarity: Par6, aPKC and cytoskeletal crosstalk.

Etienne-Manneville S, Hall A

Medline:

Citation:

Current Opinion in Cell Biology 15: 67-72 2003

Type:

REVIEW

Genes:

cdc-42 par-3 par-6 pkc-3

Abstract:

Par6 and atypical protein kinase C are key players in the establishment of cell polarity. First discovered in Caenorhabditis elegans, the function of this protein complex in all multicellular organisms. Recent work is beginning to throw light on how it converts information generated by extracellular cues into intracellular