CGC Bibliography Paper 5668

C. elegans - an innate choice?

Alfred J

Medline:
Citation:
Nature Reviews Immunology 2: 632-633 2002
Type:
REVIEW
Genes:
dbl-1 lys-1 nsy-1 pmk-1 pmk-2 sek-1
Abstract:
Much of what we know about innate immunity comes from studies in Drosophila. Two papers now show that Caenorhabditis elegans, another genetically tractable organism, might be a useful additional model for studying innate immunity. The results show that C. elegans has an inducible response to pathogen infection and that this response shares many features with innate immunity in other organisms.