CGC Bibliography Paper 5625

Developmental genomic approaches in model organisms.

Reinke V, White KP

Medline:

12142361

Citation:

Annual Review of Genomics & Human Genetics 3: 153-178 2002

Type:

REVIEW

Genes:

glp-4 pha-4

Abstract:

Functional genomics technologies can help decipher how information encoded in the genome is translated into morphology, physiology, and behavior during the development of complex organisms. A number of researchers have begun to apply DNA microarrays and other functional genomics approaches to study development. Here we review recent studies that take the first steps toward relating genome-wide information to developmental events, we discuss recent genomics approaches taken in animal model systems used to study human disease, and we outline methods that may be useful for constructing genome-wide maps of developmental processes.