CGC Bibliography Paper 5555

Engulfment mechanism of apoptotic cells.

Krieser RJ, White K

Medline:

Citation:

Current Opinion in Cell Biology 14: 734-738 2002

Type:

REVIEW

Genes:

ced-1 ced-2 ced-3 ced-5 ced-6 ced-7 ced-10 ced-12 nuc-1

Abstract:

Apoptotic cells are engulfed and removed by phagocytes. This ensures proper development of the organism and can modulate immune responses. Recent studies have examined molecules on apoptotic cells, such as phosphatidylserine, which may signal for engulfment through multiple receptors. Apoptotic recognition mechanisms may vary with the apoptotic and engulfing cell type, and even with the age of