CGC Bibliography Paper 5491
Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene.
Vargas JD,
Culetto E,
Ponting CP,
Miguel-Aliaga I,
Davies KE,
Sattelle DB
- Medline:
- 12204272
- Citation:
- Mechanisms of Development 117: 289-292 2002
- Type:
- ARTICLE
- Genes:
- ltd-1
- Abstract:
- We have characterized the developmental expression pattern of the Caenorhabditis elegans homologue of the mouse ky gene. The Ky protein has a putative key function in muscle development and has homologues in invertebrates, fungi and a cyanobacterium. The C elegans Ky homologue gene has been named ltd-1 for LIM and transglutaminase domains gene. The LTD-1::GFP construct is expressed in developing hypodermal cells from the twofold stage embryo through adulthood. These data define the ltd-1 gene as a novel marker for C. elegans epithelial cell development.