CGC Bibliography Paper 5487

Identification of 1088 new transposon insertions of Caenorhabditis elegans: a pilot study toward large-scale screens.

Martin E, Laloux H, Couette G, Alvarez T, Bessou C, Hauser O, Sokhareea S, Labouesse M, Segalat L

Medline:
12242258
Citation:
Genetics 162: 521-524 2002
Type:
ARTICLE
Genes:
Abstract:
We explored the feasibility of a strategy based on transposons to generate identified mutants of most Caenorhabditis elegans genes. A total of 1088 random new insertions of C. elegans transposons Tc1, Tc3, and Tc5 were identified by anchored PCR, some of which result in a mutant phenotype.