CGC Bibliography Paper 5426

From gene to identified neuron to behavior in Caenorhabditis elegans.

Rankin CH

Medline:

12154385

Citation:

Nature Reviews Genetics 3: 622-630 2002

Type:

REVIEW

Genes:

avr-15 daf-11 daf-21 eat-4 eat-6 egl-19 gcy-5 glr-1 gpa-9 npr-1 odr-10 osm-9 tax-2 tax-4 tpa-1 tph-1 unc-6 unc-36 unc-47

Abstract:

Understanding the role of genes in behaviour is greatly enhanced by understanding how they affect the function of the neurons that underlie behaviour. The study of behavioural genetics in Caenorhabditis elegans, an organism with a nervous system small enough to allow the role of every neuron in a given behaviour to be known, has given researchers unique insights into how genes contribute to behaviour in general. Many have taken advantage of the unique feature of this worm to analyse genes from their sequence to their role in neuronal function and, ultimately, in behaviour.