CGC Bibliography Paper 5348

Cell fusion: an EFFicient sculptor.

Witze E, Rothman JE

Medline:
12121640
Citation:
Current Biology 12: R467-R469 2002
Type:
REVIEW
Genes:
eff-1 lin-39 mab-5
Abstract:
Mutations in the eff-1 gene of Caenorhabditis elegans, which prevent all cell-cell fusions in the nematode's epidermis, have revealed developmental roles for cell fusion. An extracellular fusogen-like domain in EFF-1 suggests it might direct the fusion of lipid bilayers.