CGC Bibliography Paper 5247

MAP kinase module: the Ksr connection.

Roy F, Therrien M

Medline:

Citation:

Current Biology 12: R325-R327 2002

Type:

REVIEW

Genes:

ksr-1 ksr-2 let-60

Abstract:

Ksr has been genetically defined as a component of the Ras/MAP kinase pathway, but its role has been unclear. New studies now provide evidence that Ksr is important for signal transmission within the MAP kinase module, where it apparently acts as a location-regulated scaffold connecting MEK to Raf.