CGC Bibliography Paper 5202

Stores to die for.

Bonini NM

Medline:
11703935
Citation:
Developmental Cell 1: 447-448 2001
Type:
REVIEW
Genes:
ced-3 mec-4
Abstract:
Genes that regulate apoptosis are well defined. In contrast, it has not been clear what genes are central to necrotic cell loss. In the September 27th issue of Neuron, Xu et al. (2001) report a critical role for genes that regulate storage and release of Ca2+ from the endoplasmic reticulum as important to necrotic-like cellular degeneration in Caenorhabditis elegans.